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Comparative analysis of single-cell RNA-sequencing methods
Single-cell mRNA sequencing (scRNA-seq) allows to profile heterogeneous cell populations, offering exciting possibilities to tackle a variety of biological and medical questions. A range of methods has been recently developed, making it nece
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Single-cell RNA-Seq of cells in the early human placenta may
To treat and prevent pregnancy-related disorders, researchers must understand not only what can go wrong, but when. Complications, such as preeclampsia and pre-term birth, often occur in the second or third trimester, and most research to da
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Inertial-ordering-assisted droplet microfluidics for high-th
Single-cell RNA-seq reveals the cellular heterogeneity inherent in the population of cells, which is very important in many clinical and research applications. Recent advances in droplet microfluidics have achieved the automatic isolation, l
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Drop-seq- McCarroll Lab
Drop-seq is a technology we developed to enable biologists to analyze RNA expression genome-wide in thousands of individual cells at once. We first described this in a 2015 paper in Cell. Though commercial implementations of droplet-
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